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The TV special heralded GLP-1 agonist medications as a miracle tool for many people that could put a dent in Americas obesity epidemic, citing that Nearly one in three Americans are overweight and close to 40 percent qualify as obese. Were seeing double the amount of weight loss you can achieve with this class of medications compared to what weve had in our toolbox for the last several decades, in combination of course with a healthy lifestyle, said Amanda Velazquez, MD, director of obesity medicine at Cedars-Sinai, in the TV special